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HRID1020091

反应详情

EQUATION

反应方程式

HRID 1020091 的结构方程式

REACTANTS

反应物

2
结构：C[Si](C)(C)C=[N+]=[N-]
HCID167693

未命名化合物

结构：O=C(O)Cc1ccc(CO)cc1
HCID3283498

4-(Hydroxymethyl)phenylacetic acid

C9H10O3

PRODUCTS

生成物

1
结构：COC(=O)Cc1ccc(CO)cc1
HCID12575321

Methyl [4-(hydroxymethyl)phenyl]acetate

C10H12O3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

To 2-(4-(hydroxymethyl)phenyl)acetic acid in MeOH at 0° C. was added TMS-CHN2. The solution was stirred for 3 h then quenched with a few drops of AcOH. The solvents were evaporated. Column chromatography (SiO2, 3-15% EtOAc/Hex) gave pure methyl 2-(4-(hydroxymethyl)phenyl)acetate (E132).

WORKUP

后处理

  1. customthen quenched with a few drops of AcOH
  2. customThe solvents were evaporated