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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1020146Generated: October 26, 2026

Hydrochloric Acid → 3-Amino-2-(thiophen-3-yl)propanoic acid

https://huagongshe.com/reaction/1020146

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethyl 3-(1,3-dioxoisoindolin-2-yl)-2-(thiophen-3-yl)propanoateHCID 59161752—
Product3-Amino-2-(thiophen-3-yl)propanoic acidHCID 19756633—

Reaction Steps

To methyl 3-(1,3-dioxoisoindolin-2-yl)-2-(thiophen-3-yl)propanoate (E429) was added 6 N HCl and the solution was refluxed for 4 h. The solvents were evaporated to give 3-amino-2-(thiophen-3-yl)propanoic acid (E430).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716310B2
Source datasetuspto-grants-2014_05
ORD IDord-1adcd1f7fd1c4a55bb28d3ade82fe2d5
Source noteuspto-grants-2014_05