Tetrahydro-4H-pyran-4-one → HCID 52917035, compound

HRID 1020169Notes

Reaction equation

HRID 1020169 reaction equation
[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([NH2:15])=[N:13][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:16]1[CH2:21][CH2:20][C:19](=O)[CH2:18][CH2:17]1>>[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[CH:11][C:12]([NH:15][CH:19]3[CH2:20][CH2:21][O:16][CH2:17][CH2:18]3)=[N:13][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 121599Tetrahydro-4H-pyran-4-oneHCID 468541905-Phenylethynyl-pyridin-2-ylamine

Product 1

HCID 52917035HCID 52917035, compound

Procedure

The title compound, MS: m/e=279.3 (M+H+), can be prepared in accordance with the general method of example 13, step 2 from 5-phenylethynyl-pyridin-2-ylamine (example 13, step 1) and tetrahydro-4H-pyran-4-one.

Sources & evidence

ORD record
ord-2f50d7b8bfa8456ca0c54c1ad1778b37
Source dataset
uspto-grants-2014_05
Patent number
US08716316B2

Reaction notes

Loading…