Hydrochloric Acid → HCID 86622755, compound

Participants

Reaction Steps

[2-({2-[3-(3,4-Dichloro-benzyl)-ureido]-thiazol-4-ylmethyl}-methyl-amino)-ethyl]-carbamic acid tert-butyl ester (Example 102) was treated with HCl, 4.0M in dioxane in a similar way as Example 78 to give the title compound. 1H NMR (400 MHz, CD3OD): 7.50-7.44 (m, 2H), 7.28-7.24 (m, 2H), 4.41 (s, 4H), 3.46 (br s, 4H), 2.95 (s, 3H). MS (ES+): M/Z 388, 390 (M+1).

Provenance & Evidence