Hydrochloric Acid → tert-Butyl 6-[({4'-[2-(ethylamino) 2-oxoethyl]-1,1'-biphenyl-4-yl}oxy)methyl]-2-hydroxy-3-(trifluoromethyl)benzoate

HRID 102030Notes

Reaction equation

HRID 102030 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9]([CH2:10][O:11][c:12]2[cH:13][cH:14][c:15](-[c:18]3[cH:19][cH:20][c:21]([CH2:24][C:25](=[O:26])[OH:27])[cH:22][cH:23]3)[cH:16][cH:17]2)[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[c:31]1[OH:32].[CH2:38]([CH3:39])[NH2:40].[ClH:37]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9]([CH2:10][O:11][c:12]2[cH:13][cH:14][c:15](-[c:18]3[cH:19][cH:20][c:21]([CH2:24][C:25](=[O:26])[NH:40][CH2:38][CH3:39])[cH:22][cH:23]3)[cH:16][cH:17]2)[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[c:31]1[OH:32]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6341EthylamineHCID 11555148HCID 11555148, compound

Product 1

HCID 86617420tert-Butyl 6-[({4'-[2-(ethylamino) 2-oxoethyl]-1,1'-biphenyl-4-yl}oxy)methyl]-2-hydroxy-3-(trifluoromethyl)benzoate

Sources & evidence

ORD record
ord-ec383f8af7644a86b26c0dffdb53dcad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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