Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1020353Generated: November 4, 2026

Benzyl Bromide → 8-(5-Aminopyridin-2-yl)-2-benzyl-2,8-diazaspiro[4,5]decan-1-one

https://huagongshe.com/reaction/1020353

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant2-Chloro-5-nitropyridineHCID 78308—
Reactant2,8-Diazaspiro[4.5]decan-1-oneHCID 22225011—
Product8-(5-Aminopyridin-2-yl)-2-benzyl-2,8-diazaspiro[4,5]decan-1-oneHCID 58428992—

Reaction Steps

Intermediate B-17 was prepared by the general procedure for intermediate B-15, by using 2-chloro-5-nitropyridine, 2,8-diazaspiro[4,5]decan-1-one, and benzyl bromide as starting materials. MS (M+1): 337.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716312B2
Source datasetuspto-grants-2014_05
ORD IDord-63865aceddee4b35b852a71e6b34a1fc
Source noteuspto-grants-2014_05