Phosphorus oxychloride → HCID 20569883, compound

HRID 1020745Notes

Reaction equation

HRID 1020745 reaction equation
[CH:1]1[C:11]([Br:12])=[CH:10][C:9]2[C:3](=[N:4][C:5]([NH:7][N+:8]=2[O-:13])=O)[CH:2]=1.O=P(Cl)(Cl)[Cl:16]>>[Br:12][C:11]1[CH:1]=[CH:2][C:3]2[N:4]=[C:5]([Cl:16])[N:7]=[N+:8]([O-:13])[C:9]=2[CH:10]=1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 56772266HCID 56772266, compound

Product 1

HCID 20569883HCID 20569883, compoundYield 42%

Procedure

A solution of 7-bromo-1-oxy-benzo[1,2,4]triazin-3-ol (11 g, 46 mmol) in POCl3 (50 mL) was heated under reflux for 16 h, cooled to rt, poured into ice-water and stirred for 30 min. The mixture was filtered, washed with water and dried to afford 7-Bromo-3-chloro-benzo[1,2,4]triazine 1-oxide (5 g, 42%) as a yellow solid.

Workup

  1. temperatureunder reflux for 16 h
  2. filtrationThe mixture was filtered
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-e5ee6f044a404bbaa145f9ffd44672fc
Source dataset
uspto-grants-2014_05
Patent number
US08716473B2

Reaction notes

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