Acetonitrile → [2-(4,5-Difluoro-2-methoxy-phenyl)-6-methoxy-naphthalen-1-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone
Reaction equation
[Br:59][c:60]1[c:61]([O:68][CH3:69])[cH:62][c:63]([F:67])[c:64]([F:66])[cH:65]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8]([O:30][S:31]([C:32]([F:33])([F:34])[F:35])(=[O:36])=[O:37])[c:9]([C:13]([c:14]3[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][N:23]4[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:18][cH:19]3)=[O:29])[c:10]2[cH:11][cH:12]1.[CH3:71][C:72]#[N:73].[Cs+:58].[F-:57].[Pd:70].[c:38]1([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[cH:52][cH:53][cH:54][cH:55][cH:56]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8](-[c:60]3[c:61]([O:68][CH3:69])[cH:62][c:63]([F:67])[c:64]([F:66])[cH:65]3)[c:9]([C:13]([c:14]3[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][N:23]4[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:18][cH:19]3)=[O:29])[c:10]2[cH:11][cH:12]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-a195eaa2dc994fe1a75521ed7f1a433a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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