Acetic Acid → 4-(2,6-Difluorophenyl)-2,2-dimethyl-5-oxopiperazine-1-carboxylic acid t-butyl ester
Reaction equation
[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12]([NH:13][C:14]([CH2:15][N:16]([c:17]1[c:18]([F:24])[cH:19][cH:20][cH:21][c:22]1[F:23])[C:25]([CH2:26][Br:27])=[O:28])([CH3:29])[CH3:30])=[O:31].[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[CH3:32][C:33](=[O:34])[OH:35].[K+:6].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12]([N:13]1[C:14]([CH3:29])([CH3:30])[CH2:15][N:16]([c:17]2[c:18]([F:24])[cH:19][cH:20][cH:21][c:22]2[F:23])[C:25](=[O:28])[CH2:26]1)=[O:31]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6835ef59adfd4a2bbc682315322cd7fa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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