HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 86630519, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborate | HCID 9857522 | — |
| Reactant | 5-(9-Carboxy-nonyloxy)-isophthalic Acid Di-tert-butyl Ester | HCID 68443245 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86630519 | HCID 86630519 | — |
Reaction Steps
To a solution of 5-(9-Carboxy-nonyloxy)-isophthalic acid di-tert-butyl ester (156 mg, 0.34 mmol) in dry THF (2 ml) was added TSTU (125 mg) and DIPEA (0.08 ml). The mixture was stirred under nitrogen over night. The mixture was concentrated. The residue was redissolved in EtOAc and filtered. The filtrate was washed with 0.1N HCl (2×), and brine (1×), dried (Na2SO4) and concentrated to give a clear syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722620B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-896b0a38e55446c48d3b0592f6dbd555 |
| Source note | uspto-grants-2014_05 |