Hydrogen chloride-ethyl acetate → HCID 66975107, compound

Participants

Reaction Steps

To a solution of tert-butyl (6RS,7SR)-7-(3,4-dichlorophenyl)-6-[(sulfamoylamino)methyl]-1,4-oxazepane-4-carboxylate (202 mg) in ethanol (1 mL) was added 4 N hydrogen chloride-ethyl acetate solution (3 mL), and the mixture was stirred at room temperature for 18 hr. The crystals obtained by concentration under reduced pressure were recrystallized from ethanol-water to give the title compound (103 mg).

Provenance & Evidence