Hydrogen chloride-ethyl acetate → HCID 66980821, compound

Participants

Reaction Steps

To a solution of tert-butyl (7S)-7-(3,4-dichlorophenyl)-7-(hydroxymethyl)-1,4-oxazepane-4-carboxylate (206.2 mg) in ethanol (2 mL) was added 4 N hydrogen chloride/ethyl acetate solution (2 ml), and the mixture was stirred overnight. The solvent was evaporated under reduced pressure, and the obtained crystals were recrystallized from ethanol and ethyl acetate to give the title compound (134.5 mg).

Provenance & Evidence