HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl (6S,7R)-7-(3,4-dichlorophenyl)-6-{[(methylsulfonyl)oxy]methyl}-1,4-oxazepane-4-carboxylate → 5-cyclopropyl-1-{[(6S,7R)-7-(3,4-dichlorophenyl)-1,4-oxazepan-6-yl]methyl}-1H-pyrazole-3-carboxylic acid monohydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl (6S,7R)-7-(3,4-dichlorophenyl)-6-{[(methylsulfonyl)oxy]methyl}-1,4-oxazepane-4-carboxylate | HCID 86663851 | — |
| Reactant | HCID 178468609 | HCID 178468609 | — |
| Product | 5-cyclopropyl-1-{[(6S,7R)-7-(3,4-dichlorophenyl)-1,4-oxazepan-6-yl]methyl}-1H-pyrazole-3-carboxylic acid monohydrochloride | HCID 66976275 | — |
Reaction Steps
Using tert-butyl (6S,7R)-7-(3,4-dichlorophenyl)-6-{[(methylsulfonyl)oxy]methyl}-1,4-oxazepane-4-carboxylate and, ethyl 3-cyclopropyl-1H-pyrazole-5-carboxylate, and in the same manner as in Example 44, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722662B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-66c1741ffbd743f39845c70cfce15a75 |
| Source note | uspto-grants-2014_05 |