HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1023449Generated: October 31, 2026
Benzoyl isocyanate → 1-Benzoyl-3-{4-[2-(2-methoxy-phenyl)-ethyl]-pyridin-2-yl}-urea
https://huagongshe.com/reaction/1023449
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzoyl isocyanate | HCID 78210 | — |
| Reactant | 4-[2-(2-Methoxy-phenyl)-ethyl]-pyridin-2-ylamine | HCID 64128855 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Benzoyl-3-{4-[2-(2-methoxy-phenyl)-ethyl]-pyridin-2-yl}-urea | HCID 69082396 | — |
Reaction Steps
Benzoyl isocynate (132 mg, 0.896 mmol) is added to a solution of 4-[2-(2-methoxy-phenyl)-ethyl]-pyridin-2-ylamine (93.0 mg, 0.407 mmol) in CH2Cl2 (4 mL), and the mixture is stirred at 60° C. After 20 hours, the mixture is concentrated to give the crude product, which is used in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08722709B2 |
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| Source dataset | uspto-grants-2014_05 |
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| ORD ID | ord-36df7a69ddeb4024b67e58e1391b5b44 |
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| Source note | uspto-grants-2014_05 |
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