Trifluoroacetic acid → HCID 86693757, compound

Participants

Reaction Steps

Trifluoroacetic acid (5 mL) was added to a dichloromethane (5 mL) solution of the obtained tert-butyl 4-(5-{(1R)-1-[4-(cyclobutylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzoate at room temperature, and the mixture was stirred for one hour. The solvent was distilled off under reduced pressure, and the resulting residue was solidified by using hexane:ethyl acetate (5:1, v/v). Thus, the title compound (531 mg, yield: 56%) was obtained.

Provenance & Evidence