HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 66559253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | N-Methyl-D-glucamine | HCID 8567 | — |
| Reactant | Raltegravir | HCID 54671008 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 66559253 | HCID 66559253 | — |
Reaction Steps
A three necked round bottom flask (50 ml) was charged with Raltegravir free hydroxy (300 mg), Meglumine (132 mg), THF (15 mL) and water (7.5 mL) to obtain a mixture. The mixture was stirred at room temperature, yellow clear solution was obtained. The solution was evaporated and dried overnight in a vacuum oven at 60° C. The resulting product was characterised by XRPD.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722722B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-235f8631e023415f8070b81fbe21dd83 |
| Source note | uspto-grants-2014_05 |