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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1023684Generated: November 2, 2026

Tetrahydrofuran → HCID 66559253, compound

https://huagongshe.com/reaction/1023684

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantN-Methyl-D-glucamineHCID 8567—
ReactantRaltegravirHCID 54671008—
SolventWaterHCID 962—
ProductHCID 66559253HCID 66559253—

Reaction Steps

A three necked round bottom flask (50 ml) was charged with Raltegravir free hydroxy (300 mg), Meglumine (132 mg), THF (15 mL) and water (7.5 mL) to obtain a mixture. The mixture was stirred at room temperature, yellow clear solution was obtained. The solution was evaporated and dried overnight in a vacuum oven at 60° C. The resulting product was characterised by XRPD.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08722722B2
Source datasetuspto-grants-2014_05
ORD IDord-235f8631e023415f8070b81fbe21dd83
Source noteuspto-grants-2014_05