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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1023693Generated: October 26, 2026

Aniline → HCID 67045287, compound

https://huagongshe.com/reaction/1023693

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
ReactantEthyl 4-(4-aminophenyl)butanoateHCID 10013251—
ReactantMethyl 2-(bromomethyl)-5-nitrobenzoateHCID 14552709—
ProductHCID 67045287HCID 67045287—

Reaction Steps

By using 2-bromomethyl-5-nitrobenzoic acid methyl ester and 4-(4-amino-phenyl)butyric acid ethyl ester instead of 2-bromomethyl-6-nitro-benzoic acid methyl ester and aniline used in Example 25, synthesis was performed in the same manner as that of Example 25 to obtain 4-[4-(6-nitro-1-oxo-1,3-dihydro-isoindol-2-yl)-phenyl]-butyric acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08722723B2
Source datasetuspto-grants-2014_05
ORD IDord-4d0b073f327d469ca1b1ecd68f75a21a
Source noteuspto-grants-2014_05