Methyl 5-aminopyridine-2-carboxylate → HCID 67396482, compound

Participants

Reaction Steps

In the same manner as that of Example 2, 4,5-diisopropylthiophene-2-carboxylic acid (102 mg, 0.481 mmol) was condensed with methyl 5-aminopyridine-2-carboxylate, and the resultant was purified by silica gel chromatography [benzene-ethyl acetate (2:1)] to obtain methyl 5-[(4,5-diisopropylthiophene-2-carbonyl)amino]pyridine-2-carboxylate (112 mg, 67%) as colorless needles.

Provenance & Evidence