Lithium Hydroxide → HCID 67395289, compound

HRID 1023730Notes

Reaction equation

HRID 1023730 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][C:14]([CH2:16][NH:17][C:18]2[CH:19]=[C:20]([CH:26]=[CH:27][CH:28]=2)[C:21]([O:23]CC)=[O:22])=[O:15])[O:7][C:8]=1[CH:9]([CH3:11])[CH3:10])([CH3:3])[CH3:2].[OH-].[Li+]>>[CH:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][C:14]([CH2:16][NH:17][C:18]2[CH:19]=[C:20]([CH:26]=[CH:27][CH:28]=2)[C:21]([OH:23])=[O:22])=[O:15])[O:7][C:8]=1[CH:9]([CH3:10])[CH3:11])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 67394962HCID 67394962, compound

Product 1

HCID 67395289HCID 67395289, compoundYield 94.2%

Procedure

This ester (94 mg, 0.245 mmol) was hydrolyzed with lithium hydroxide in a conventional manner, and the residue was recrystallized to obtain the title compound (29, 82 mg, 94%) as colorless prisms.

Workup

  1. customthe residue was recrystallized

Sources & evidence

ORD record
ord-3bec60f698c24850910b2cf5e754720b
Source dataset
uspto-grants-2014_05
Patent number
US08722730B2

Reaction notes

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