Lithium Hydroxide → HCID 67394637, compound

HRID 1023732Notes

Reaction equation

HRID 1023732 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([C:12]([NH:14][C:15]2[O:19][C:18]([C:20]([O:22]C)=[O:21])=[CH:17][CH:16]=2)=[O:13])[O:7][C:8]=1[CH:9]([CH3:11])[CH3:10])([CH3:3])[CH3:2].[OH-].[Li+]>>[CH:1]([C:4]1[CH:5]=[C:6]([C:12]([NH:14][C:15]2[O:19][C:18]([C:20]([OH:22])=[O:21])=[CH:17][CH:16]=2)=[O:13])[O:7][C:8]=1[CH:9]([CH3:11])[CH3:10])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 67394175HCID 67394175, compound

Product 1

HCID 67394637HCID 67394637, compoundYield 75%

Procedure

This ester (42 mg, 0.132 mmol) was hydrolyzed with lithium hydroxide in a conventional manner, and then the residue was recrystallized to obtain the title compound (35, 30 mg, 75%) as pale yellow prisms.

Workup

  1. customthe residue was recrystallized

Sources & evidence

ORD record
ord-b9e46e5a820249a59d341f09d6c04b61
Source dataset
uspto-grants-2014_05
Patent number
US08722730B2

Reaction notes

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