Lithium Hydroxide → HCID 67395498, compound

HRID 1023734Notes

Reaction equation

HRID 1023734 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([C:12]([NH:14][C:15]2[CH:16]=[C:17]3[C:21](=[CH:22][CH:23]=2)[NH:20][C:19]([C:24]([O:26]CC)=[O:25])=[CH:18]3)=[O:13])[O:7][C:8]=1[CH:9]([CH3:11])[CH3:10])([CH3:3])[CH3:2].[OH-].[Li+]>>[CH:1]([C:4]1[CH:5]=[C:6]([C:12]([NH:14][C:15]2[CH:16]=[C:17]3[C:21](=[CH:22][CH:23]=2)[NH:20][C:19]([C:24]([OH:26])=[O:25])=[CH:18]3)=[O:13])[O:7][C:8]=1[CH:9]([CH3:11])[CH3:10])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 67395583HCID 67395583, compound

Product 1

HCID 67395498HCID 67395498, compoundYield 94%

Procedure

This ester (38 mg, 99.5 μmol) was hydrolyzed with lithium hydroxide in a conventional manner, and then the residue was recrystallized to obtain the title compound (36, 33 mg, 94%) as colorless prisms.

Workup

  1. customthe residue was recrystallized

Sources & evidence

ORD record
ord-af5ebd47df2e49d99b7c4cc2306ecd51
Source dataset
uspto-grants-2014_05
Patent number
US08722730B2

Reaction notes

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