反应详情

温度

20 °C

Morpholine (1.1 ml) was added to a solution of [4-bromo-2-(trifluoromethyl)phenyl]sulfonyl chloride (2.03 g) in DCM (7 ml) at 0° C. and stirred at 20° C. for 16 h. Water was added and the mixture was extracted with DCM. The organic extracts were dried (MgSO4), evaporated and purified by chromatography (silica, petrol-ether as eluent) to give the sub-title compound 2.10 g).

1. extractionthe mixture was extracted with DCM
2. dry with materialThe organic extracts were dried (MgSO4)
3. customevaporated
4. custompurified by chromatography (silica, petrol-ether as eluent)