Lithium hydroxide, monohydrate → HCID 178524385, compound

HRID 1023839Notes

Reaction equation

HRID 1023839 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:24]=[CH:23][CH:22]=[CH:21][C:7]=2[O:8][CH2:9][C:10]2[CH:20]=[CH:19][C:13]([C:14]([O:16]CC)=[O:15])=[CH:12][CH:11]=2)[N:3]=[CH:2]1.O[Li:26].O>CO.O>[NH:1]1[CH:5]=[C:4]([C:6]2[CH:24]=[CH:23][CH:22]=[CH:21][C:7]=2[O:8][CH2:9][C:10]2[CH:20]=[CH:19][C:13]([C:14]([O-:16])=[O:15])=[CH:12][CH:11]=2)[N:3]=[CH:2]1.[Li+:26]

Participants

5

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 178468930HCID 178468930, compound

Product 1

HCID 178524385HCID 178524385, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

Ethyl 4-((2-(1H-imidazol-4-yl)phenoxy)methyl)benzoate (0.33 mmol, 105 mg) was diluted with MeOH (3 mL) and water (1 mL) followed by the addition of LiOH.H2O (0.33 mmol, 14.35 mg). After stirring for 4 h at room temperature, the solvent was removed under vacuum to afford the product.

Workup

  1. customthe solvent was removed under vacuum
  2. customto afford the product

Sources & evidence

ORD record
ord-cc0ce0a6d80345f3a236da136668685c
Source dataset
uspto-grants-2014_05
Patent number
US08722720B2

Reaction notes

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