HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1023896Generated: October 27, 2026
Potassium Carbonate → 2-[2-(Benzyloxy)-4-ethylphenoxy]-6-fluoropyridine
https://huagongshe.com/reaction/1023896
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,6-Difluoropyridine | HCID 73934 | — |
| Reactant | 2-(Benzyloxy)-4-ethylphenol | HCID 59191243 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 2-[2-(Benzyloxy)-4-ethylphenoxy]-6-fluoropyridine | HCID 59191354 | — |
Reaction Steps
To a suspension of K2CO3 (0.25 mmol; 35 mg) in anhydrous acetonitrile (2 mL) under argon, was added 2-Benzyloxy-4-ethyl-phenol (48 mg; 0.21 mmol) followed by 2,6-difluoropyridine (100 μL; 1.10 mmol). The reaction mixture was stirred at 80° C. overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08722746B2 |
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| Source dataset | uspto-grants-2014_05 |
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| ORD ID | ord-3e26ca6d6aa2466da188281bcffd0b29 |
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| Source note | uspto-grants-2014_05 |
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