Tetrahydrofuran → HCID 59191291, compound

HRID 1023933Notes

Reaction equation

HRID 1023933 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[N+:16]([O-])=O)=[C:5]([O:19][CH3:20])[CH:4]=1)[CH3:2].C1COCC1>C(O)C>[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH2:16])=[C:5]([O:19][CH3:20])[CH:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 8028TetrahydrofuranHCID 59191352HCID 59191352, compound

Product 1

HCID 59191291HCID 59191291, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

According to the procedure of example 20(b) except substituting 4-ethyl-2-methoxy-1-[4-nitro-2-(trifluoromethyl)phenoxy]benzene by 4-ethyl-2-methoxy-1-(2-nitrophenoxy)benzene (0.66 mmol; 180 mg) and THF by ethanol, the title compound was prepared in quantitative yield (181 mg) and used without further purification.

Workup

  1. customused without further purification

Sources & evidence

ORD record
ord-3a26f309d76d4d149cbfeb4306ebfeb2
Source dataset
uspto-grants-2014_05
Patent number
US08722746B2

Reaction notes

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