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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1023940Generated: October 30, 2026

Tetrahydrofuran → HCID 59191363, compound

https://huagongshe.com/reaction/1023940

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 59191258HCID 59191258—
SolventEthanolHCID 702—
ProductHCID 59191363HCID 59191363—

Reaction Steps

According to the procedure of example 20(b) except substituting 4-ethyl-2-methoxy-1-[4-nitro-2-(trifluoromethyl)phenoxy]benzene for 4-ethyl-1-(2-fluoro-4-nitrophenoxy)-2-methoxybenzene (1.16 g; 4.0 mmol) and tetrahydrofurane for ethanol (16 mL), two compounds were obtained after purification on silica gel (gradient cyclohexane/dichloromethane) 4-(4-ethyl-2-methoxyphenoxy)-3-fluoroaniline (466 mg; 45%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08722746B2
Source datasetuspto-grants-2014_05
ORD IDord-2802a45a37dc493db7a39cfe87a22203
Source noteuspto-grants-2014_05