HRID1024025

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID46835269

8-Bromo-6-chloroimidazo[1,2-b]pyridazine

C6H3BrClN3

结构：CN1CCN(c2ccc(Nc3cc(Cl)nn4ccnc34)nc2)CC1

HCID86684123

未命名化合物

HCID86684125

5-[4-(3-Oxetanyl)-1-piperazinyl]-2-pyridinamine

C12H18N4O

PRODUCTS

生成物

结构：Clc1cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c2nccn2n1

HCID86684124

未命名化合物

收率 77%

PROCEDURE

实验过程

Following the procedures as described for compound 104b, 8-bromo-6-chloroimidazo[1,2-b]pyridazine 104a (233 mg, 1.0 mmol), and 5-(4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-amine (234 mg, 1.0 mmol) were reacted to give 105a as a white solid (296 mg, 77%). LCMS: [M+H]+ 386

WORKUP

后处理

customwere reacted