Hydrochloric Acid → HCID 145734634, compound

Participants

Reaction Steps

1.4 595 μl of 2 N NaOH are added to a suspension of 112 mg of “A1” in 1.5 ml of methanol, and the mixture is stirred at 60° for 3 hours. The mixture is cooled, 0.7 ml of 2 N HCl is added, the mixture is diluted with water, the precipitate is removed, and the mixture is subjected to conventional work-up, giving 75 mg of 3-benzyl-6-hydroxy-1H-indazole-5-carboxylic acid (“A2”).

Provenance & Evidence