HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 152782811, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 148095122 | HCID 148095122 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 152782811 | HCID 152782811 | — |
Reaction Steps
4.5 4.23 ml of 2 N NaOH are added to a solution of 523 mg of “4d” in 10 ml of dioxane, and the mixture is heated under reflux for 1.5 hours. The mixture is subjected to conventional work-up, giving 386 mg of 5-carboxy-6-hydroxy-3-(3-methylbenzyl)-1H-indazole (“4e”).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722903B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-c95dac44ae7d483ab415c01328e84460 |
| Source note | uspto-grants-2014_05 |