反应详情

温度

40 °C

To a solution of 1 mmol 14-(furan-2-yl)tetradeca-11,13-diynoic acid in water, 1 m molar aqueous potassium hydroxide was added at room temperature with stirring. After 2-3 hours the reaction mixture was concentrated under reduced pressure. The crude product was dissolved in acetone and heated to 40° C. for 10 min, then the solid product filtered off and washed several times with acetone. The resultant solid product was evaporated under reduced pressure yielding potassium 14-(furan-2-yl)tetradeca-11,13-diynoate. The sodium salt 14-(furan-2-yl)tetradeca-11,13-diynoate (XI″) was achieved in like manner from 14-(furan-2-yl)tetradeca-11,13-diynoic acid.

1. concentrationAfter 2-3 hours the reaction mixture was concentrated under reduced pressure
2. dissolutionThe crude product was dissolved in acetone
3. filtrationthe solid product filtered off
4. washwashed several times with acetone
5. customThe resultant solid product was evaporated under reduced pressure