Potassium Hydroxide → Potassium 14-(furan-2-yl)tetradeca-11,13-diynoate

Participants

Reaction Conditions

Reaction Steps

To a solution of 1 mmol 14-(furan-2-yl)tetradeca-11,13-diynoic acid in water, 1 m molar aqueous potassium hydroxide was added at room temperature with stirring. After 2-3 hours the reaction mixture was concentrated under reduced pressure. The crude product was dissolved in acetone and heated to 40° C. for 10 min, then the solid product filtered off and washed several times with acetone. The resultant solid product was evaporated under reduced pressure yielding potassium 14-(furan-2-yl)tetradeca-11,13-diynoate. The sodium salt 14-(furan-2-yl)tetradeca-11,13-diynoate (XI″) was achieved in like manner from 14-(furan-2-yl)tetradeca-11,13-diynoic acid.

Provenance & Evidence