Glycerol → DL-3-n-Butylphthalide

HRID 1025247Notes

Reaction equation

HRID 1025247 reaction equation
O[CH2:2][CH:3]([CH2:5]O)O.[CH2:7]([O:9][C:10]([C:12]1[CH:18]=[CH:17][C:15](O)=[CH:14][CH:13]=1)=[O:11])[CH3:8]>O>[CH2:8]([CH:7]1[C:18]2[C:12](=[CH:13][CH:14]=[CH:15][CH:17]=2)[C:10](=[O:11])[O:9]1)[CH2:2][CH2:3][CH3:5]

Participants

4

Reactant 2

HCID 753GlycerolHCID 8434Ethylparaben

Product 1

HCID 61361DL-3-n-Butylphthalide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

100 g of gelatin, 40 g of glycerin, 120 g of water and 200 mg of ethylparaben are used. The gelatin solution is prepared by the same protocol as in Example 1.

Workup

  1. customThe gelatin solution is prepared by the same protocol as in Example 1

Sources & evidence

ORD record
ord-72ab5d940e704a0fab3191dda3a213f4
Source dataset
uspto-grants-2014_05
Patent number
US08728518B2

Reaction notes

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