Hydrochloric Acid → (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride

関与物質

反応手順

Under an atmosphere of argon, tert-butyl (2S,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxopentan-3-ylcarbamate (540 mg, 1.98 mmol) and HCl 4N in dioxane (10.4 ml) were combined to give a light brown solution. The reaction was stirred for 4 h at RT. The solvent was evaporated. The residual solvent was removed under vacuum. The title compound was obtained as a brown solid (480 mg, quant., MS (m/e)=173.2 [M+H+].

情報源と証拠