HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azepane → 2-(3-(Azepan-1-yl)propyl)isoindoline-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azepane | HCID 8119 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-3-Bromopropylphthalimide | HCID 21611 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2-(3-(Azepan-1-yl)propyl)isoindoline-1,3-dione | HCID 58540561 | — |
Reaction Steps
The mixture of Azepane (2.3 mL), 2-(3-bromopropyl)isoindoline-1,3-dione (5.4 g) and potassium carbonate (5.5 g) in acetone (50 mL) was stirred at room temperature overnight. The solid was filtered and the filtrate was concentrated to provide 2-(3-(azepan-1-yl)propyl)isoindoline-1,3-dione, used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729081B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-3e57c933f8194d9ab5f985bd39c5b928 |
| Source note | uspto-grants-2014_05 |