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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025499Generated: October 31, 2026

2-Chloro-5-propylpyrimidine → 2-(4-(5-Bromo-7-fluoro-2,3-dihydrobenzofuran-2-yl)piperidin-1-yl)-5-propylpyrimidine

https://huagongshe.com/reaction/1025499

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-propylpyrimidineHCID 2735784—
Reactant4-(5-Bromo-7-fluoro-2,3-dihydrobenzofuran-2-yl)-1-(5-propylpyrimidin-2-yl)piperidin-4-olHCID 67465774—
Reactant4-(5-Bromo-7-fluoro-2,3-dihydrobenzofuran-2-yl)piperidineHCID 68211894—
Product2-(4-(5-Bromo-7-fluoro-2,3-dihydrobenzofuran-2-yl)piperidin-1-yl)-5-propylpyrimidineHCID 68211530—

Reaction Steps

Compound 3F was prepared from Compound 3E and 2-chloro-5-propylpyrimidine in a similar manner to the procedure described in Compound 1H, Example 1. LC/MS (m/z)=421 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729084B2
Source datasetuspto-grants-2014_05
ORD IDord-b75c306653414fd8be20ffe15fa02e88
Source noteuspto-grants-2014_05