Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | methyl 4-bromo-1-methyl-1H-imidazole-2-carboxylate | HCID 53302209 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 71008280 | HCID 71008280 | 100% |
Reaction Steps
To the saturated solution of ammonia in MeOH was added 165 mg of 4-bromo-1-methyl-1H-imidazole-2-carboxylic acid methyl ester and the resulting mixture was stirred at 20° C. for 16 h. The solution was evaporated to give 4-bromo-1-methyl-1H-imidazole-2-carboxylic acid amide (154 mg, yield 100%). LC-MS calcd for C5H6BrN3O (m/e) 202.97, obsd 204 and 206 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08729078B2 |
|---|
| Source dataset | uspto-grants-2014_05 |
|---|
| ORD ID | ord-4d9f8370063647669c10e393382f8540 |
|---|
| Source note | uspto-grants-2014_05 |
|---|
