Dimethylformamide → Methyl 3-[4-(5-chloro-1-methyl-2-oxo-3-pyridinyl)phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
Reaction equation
[Br:1][c:2]1[c:3](=[O:10])[n:4]([CH3:9])[cH:5][c:6]([Cl:8])[cH:7]1.[CH3:11][O:12][C:13]([CH:14]([NH:15][C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:23][c:24]1[cH:25][cH:26][c:27]([Sn:30]([CH2:31][CH2:32][CH2:33][CH3:34])([CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH2:41][CH3:42])[cH:28][cH:29]1)=[O:43].[Cl:49][CH2:50][Cl:51].[O:44]=[CH:45][N:46]([CH3:47])[CH3:48].[cH:52]1[cH:53][cH:54][c:55]([P:56]([Pd:57]([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)([P:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[P:96]([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)([c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[cH:127][cH:128]1>>[c:2]1(-[c:27]2[cH:26][cH:25][c:24]([CH2:23][CH:14]([C:13]([O:12][CH3:11])=[O:43])[NH:15][C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[cH:29][cH:28]2)[c:3](=[O:10])[n:4]([CH3:9])[cH:5][c:6]([Cl:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cc526079ca714fbab594e047d680397e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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