HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-2-methoxypyridine → HCID 67320324, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-2-methoxypyridine | HCID 2737488 | — |
| Reactant | [4-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone | HCID 53311781 | — |
| Product | HCID 67320324 | HCID 67320324 | — |
Reaction Steps
The title compound was prepared in analogy to Example 1, from 4-(2,5-dichloro-phenoxy)-nicotinic acid (Example 1, intermediate) and 3-amino-2-methoxypyridine (commercially available, CAS RN 20265-38-7). The compound was purified by preparative HPLC (Phenomenex Gemini column) using a gradient of acetonitrile:water (10:90 to 95:5). Light brown solid (28%). MS (ESI): m/z=390.040 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729091B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-22e02cf9c6ad408ea4e0f68693c29cce |
| Source note | uspto-grants-2014_05 |