HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Piperidin-1-yl)aniline → 4-(2,5-Dichloro-phenoxy)-N-(2-piperidin-1-yl-phenyl)-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Piperidin-1-yl)aniline | HCID 458795 | — |
| Reactant | [4-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone | HCID 53311781 | — |
| Product | 4-(2,5-Dichloro-phenoxy)-N-(2-piperidin-1-yl-phenyl)-nicotinamide | HCID 67319857 | — |
Reaction Steps
The title compound was prepared in analogy to Example 1, from 4-(2,5-dichloro-phenoxy)-nicotinic acid (Example 1, intermediate) and 2-piperidin-1-yl-phenylamine (commercially available; CAS RN 39643-31-7). White foam (90%). MS (ESI): 442.108 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729091B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-93c6373cec0b4172900c767b0874cffd |
| Source note | uspto-grants-2014_05 |