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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025986Generated: November 3, 2026

(4-Chloro-2-fluorophenyl)boronic acid → HCID 66678488, compound

https://huagongshe.com/reaction/1025986

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chloro-2-fluorophenyl)boronic acidHCID 4193595—
ReactantMethyl 5-bromo-6-(2,2,2-trifluoroethoxy)nicotinateHCID 66686828—
ProductHCID 66678488HCID 66678488—

Reaction Steps

The title compound was synthesized in analogy to Examples BI to BJ using 5-bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid methyl ester (CAN 1211589-51-3) and B-(4-chloro-2-fluorophenyl)-boronic acid, (CAN 160591-91-3) as starting materials; LC-MS (UV peak area/ESI) 98.8%, 348.0061 (M−H)−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729105B2
Source datasetuspto-grants-2014_05
ORD IDord-a1fd52405ba14b8794c2f38c9ecfc4ed
Source noteuspto-grants-2014_05