HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid → 6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid (2-cyclopropyl-oxazol-4-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 66678605 | — |
| Reactant | (2-Cyclopropyl-1,3-oxazol-4-yl)methanamine | HCID 66678609 | — |
| Product | 6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid (2-cyclopropyl-oxazol-4-ylmethyl)-amide | HCID 56928905 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 41, using 6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid (example AW) and 2-cyclopropyl-4-oxazolmethanamine (example BH) as starting materials, LC-MS (UV peak area/ESI) 97.6%, 424.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729105B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-5eb5e5af9c3c4a2488715a0ba529bc1b |
| Source note | uspto-grants-2014_05 |