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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026229Generated: October 31, 2026

Methanol → HCID 67778809, compound

https://huagongshe.com/reaction/1026229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantHCID 67776616HCID 67776616—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 67778809HCID 67778809104%

Reaction Steps

Under a hydrogen atmosphere, a mixture of 2-[4-(benzyloxy)phenyl]-5-methoxy-2H-indazole (160 mg), 10% palladium/carbon (containing water (50%), 52 mg), methanol (10 mL) and THF (5 mL) was stirred at room temperature for 1 hr. The catalyst was removed by filtration, and the obtained filtrate was concentrated under reduced pressure to give the title compound (121 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729102B2
Source datasetuspto-grants-2014_05
ORD IDord-f22c9f014d074c94bc209b2ebc25d6c6
Source noteuspto-grants-2014_05