HCID 86666274, compound → HCID 86666275, compound

Participants

Reaction Steps

Under a hydrogen atmosphere, a mixture of tert-butyl [(1S)-2-(3-fluoro-4-nitrophenoxy)-1-methylethyl]carbamate (10.2 g), 10% palladium/carbon (containing water (50%), 500 mg) and ethanol (150 mL) was stirred at room temperature for 1 hr. The catalyst was removed by filtration, and the obtained filtrate was concentrated under reduced pressure to give the title compound as a brown solid (8.64 g).

Provenance & Evidence