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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026261Generated: October 30, 2026

1132843-09-4 → tert-butyl {(1S)-2-[(6-{6-[(3,3-difluorocyclobutyl)methoxy]-1,3-benzoxazol-2-yl}pyridin-3-yl)oxy]-1-methylethyl}carbamate

https://huagongshe.com/reaction/1026261

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1132843-09-4HCID 58223412—
Reactanttert-butyl [(1S)-2-{[6-(6-hydroxy-1,3-benzoxazol-2-yl)pyridin-3-yl]oxy}-1-methylethyl]carbamateHCID 136372364—
Producttert-butyl {(1S)-2-[(6-{6-[(3,3-difluorocyclobutyl)methoxy]-1,3-benzoxazol-2-yl}pyridin-3-yl)oxy]-1-methylethyl}carbamateHCID 86666283—

Reaction Steps

Using tert-butyl [(1S)-2-{[6-(6-hydroxy-1,3-benzoxazol-2-yl)pyridin-3-yl]oxy}-1-methylethyl]carbamate and (3,3-difluorocyclobutyl)methyl methanesulfonate, and in the same manner as in Example 2, step E, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729102B2
Source datasetuspto-grants-2014_05
ORD IDord-9e15a53a5fed449cbe5809a145d973cf
Source noteuspto-grants-2014_05