Benzyl Bromide → HCID 67777572, compound

HRID 1026275Notes

Reaction equation

[Br:1][C:2]1[C:3]([O:11][CH2:12][C@@H:13]([NH:15][C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH3:14])=[N:4][NH:5][C:6]=1[C:7]([O:9][CH3:10])=[O:8].[CH2:23](Br)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([N:5]1[C:6]([C:7]([O:9][CH3:10])=[O:8])=[C:2]([Br:1])[C:3]([O:11][CH2:12][C@@H:13]([NH:15][C:16]([O:18][C:19]([CH3:21])([CH3:20])[CH3:22])=[O:17])[CH3:14])=[N:4]1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 67777124HCID 67777124, compound

Product 1

HCID 67777572HCID 67777572, compound

Procedure

Using methyl 4-bromo-3-({(2S)-2-[(tert-butoxycarbonyl)amino]propyl}oxy)-1H-pyrazole-5-carboxylate and benzyl bromide, and in the same manner as in Example 1, step A, the title compound was obtained.

Sources & evidence

ORD record: ord-559a80fb81e545bcb89c82accdc11b8a
Source dataset: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08729102B2

Reaction notes

Loading…