HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzene-1,3-diol hydrochloride → tert-butyl [(1S)-2-({5-[(2,4-dihydroxyphenyl)carbamoyl]isoxazol-3-yl}oxy)-1-methylethyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzene-1,3-diol hydrochloride | HCID 13408822 | — |
| Reactant | 3-({(2S)-2-[(tert-butoxycarbonyl)amino]propyl}oxy)isoxazole-5-carboxylic acid | HCID 67777715 | — |
| Product | tert-butyl [(1S)-2-({5-[(2,4-dihydroxyphenyl)carbamoyl]isoxazol-3-yl}oxy)-1-methylethyl]carbamate | HCID 86666289 | — |
Reaction Steps
Using 3-({(2S)-2-[(tert-butoxycarbonyl)amino]propyl}oxy)isoxazole-5-carboxylic acid and 4-aminobenzene-1,3-diol hydrochloride, and in the same manner as in Example 2, step C, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729102B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-55cb9b35daa2485480f75b3b9702c892 |
| Source note | uspto-grants-2014_05 |