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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1026289Generated: November 2, 2026

Iodoethane → tert-butyl [(1S)-2-{[6-(6-ethoxy-1,3-benzoxazol-2-yl)-5-fluoropyridin-3-yl]oxy}-1-methylethyl]carbamate

https://huagongshe.com/reaction/1026289

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactanttert-butyl [(1S)-2-({6-[(2,4-dihydroxyphenyl)carbamoyl]-5-fluoropyridin-3-yl}oxy)-1-methylethyl]carbamateHCID 86666268—
Producttert-butyl [(1S)-2-{[6-(6-ethoxy-1,3-benzoxazol-2-yl)-5-fluoropyridin-3-yl]oxy}-1-methylethyl]carbamateHCID 86666294—

Reaction Steps

Using tert-butyl [(1S)-2-({6-[(2,4-dihydroxyphenyl)carbamoyl]-5-fluoropyridin-3-yl}oxy)-1-methylethyl]carbamate and ethyl iodide, and in the same manner as in Example 2, steps D-E, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729102B2
Source datasetuspto-grants-2014_05
ORD IDord-5aaf32e398174ec0a2f6b68e70c6f046
Source noteuspto-grants-2014_05