2,6-Dimethylaniline → HCID 58409410, compound

HRID 1026365Notes

Reaction equation

HRID 1026365 reaction equation
[CH3:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:3]=1[NH2:4].Br[C:11]1[CH:12]=[CH:13][CH:14]=[C:15]2[C:20]=1[N:19]=[C:18]([CH3:21])[CH:17]=[C:16]2[CH3:22]>>[CH3:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:3]=1[NH:4][C:11]1[CH:12]=[CH:13][CH:14]=[C:15]2[C:20]=1[N:19]=[C:18]([CH3:21])[CH:17]=[C:16]2[CH3:22]

Participants

3

Reactant 2

HCID 68962,6-DimethylanilineHCID 33698220HCID 33698220, compound

Product 1

HCID 58409410HCID 58409410, compoundYield 46%

Procedure

Repeat the procedure of Example 1 except use 2,6-dimethylaniline instead of 2,6-diisopropylaniline and 8-bromo-2,4-dimethylquinoline instead of 8-bromoquinoline to give purified (4) in 46% yield.

Workup

  1. customto give
  2. custompurified (4) in 46% yield

Sources & evidence

ORD record
ord-ef1927403aa043cdb10b9cf34722045d
Source dataset
uspto-grants-2014_05
Patent number
US08729201B2

Reaction notes

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