Bicarbonate Ion → 3-Chloro-5-(4-chlorophenyl)-4-(pyridin-4-yl)pyridazine

HRID 102648Notes

Reaction equation

HRID 102648 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:15]3[cH:16][cH:17][n:18][cH:19][cH:20]3)[c:10](=[O:14])[nH:11][n:12][cH:13]2)[cH:6][cH:7]1.[Na+:30].[O-:26][C:27]([OH:28])=[O:29].[OH2:31].[P:21]([Cl:22])([Cl:23])([Cl:24])=[O:25]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:15]3[cH:16][cH:17][n:18][cH:19][cH:20]3)[c:10]([Cl:23])[n:11][n:12][cH:13]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 24813Phosphorus oxychlorideHCID 597167155-(4-chlorophenyl)-4-(pyridin-4-yl)pyridazin-3(2H)-one

Product 1

HCID 597168553-Chloro-5-(4-chlorophenyl)-4-(pyridin-4-yl)pyridazine

Sources & evidence

ORD record
ord-a043abfb51794f6ca95901ac131bda84
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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