4,6-Dichloro-5-(2-chloro-5-methoxy-phenoxy)-pyrimidine → Benzylsulfamic acid [6-chloro-5-(2-chloro-5-methoxy-phenoxy)-pyrimidin-4-yl]-amide

Participants

Role	Name	HCID	Charge
Reactant	4,6-Dichloro-5-(2-chloro-5-methoxy-phenoxy)-pyrimidine	HCID 21979566	—
Reactant	Benzylsulfamic acid amide potassium salt	HCID 68727905	—
Product	Benzylsulfamic acid [6-chloro-5-(2-chloro-5-methoxy-phenoxy)-pyrimidin-4-yl]-amide	HCID 21041375	47%

Reaction Steps

Benzylsulfamic acid [6-chloro-5-(2-chloro-5-methoxy-phenoxy)-pyrimidin-4-yl]-amide (0.7 g) was prepared from 4,6-dichloro-5-(2-chloro-5-methoxy-phenoxy)-pyrimidine (1 g) and benzylsulfamic acid amide potassium salt (1.21 g) according to the procedure described in Referential Example 15. LC-MS: tR=5.13; [M+H]+=456.91.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07094781B2
Source dataset	uspto-grants-2006_08
ORD ID	ord-829e83a9265c4f86b928d2636b829e73
Source note	uspto-grants-2006_08